Therapeutic Areas

Acute Hepatic Porphyria (AHP)
Acute Hepatic Porphyria (AHP)
Transthyretin (ATTR) Amyloidosis
Transthyretin Amyloidosis (ATTR)
Primary Hyperoxaluria Type 1 (PH1)
Primary Hyperoxaluria Type 1 (PH1)
Neurologic
Neurologic
Cardiovascular (CV)
Cardiovascular (CV)

 Science of RNAi

RNAi Mechanism of Action RNAi Mechanism of Action

Image
Video Icon

Video

RNAi Mechanism of Action

This video highlights the mechanism of action (MOA) of RNAi therapeutics and its role in silencing gene expression. This video is intended to be viewed in its entirety.

View more on Alnylam & RNAi Science 

Congresses

Congress-HFA

Transthyretin Amyloidosis (ATTR)

Heart Failure Association (HFA) 2026

Congress-AAN

Acute Hepatic Porphyria (AHP)

Digestive Disease Week (DDW) 2026

Congress-Boston

Primary Hyperoxaluria Type 1 (PH1)

Pediatric Academic Societies (PAS) 2026

Publications

Transthyretin Amyloidosis (ATTR)

Best Practices and Key Barriers for Amyloidosis Patient Care at US Specialized Amyloidosis Centers: An Analysis by ARC-ASPIRE

Clinical Medicine Insights: Cardiology

Author(s)

Jose Nativi-Nicolau, Johana Fajardo, Alyssa Galloway, et al

Transthyretin Amyloidosis (ATTR)

Effect of vutrisiran on components of health status in transthyretin amyloidosis with cardiomyopathy: the HELIOS-B study

European Journal of Heart Failure

Author(s)

Yasuhiro Hamatani, Brian L Claggett, Muthiah Vaduganathan, et al

Transthyretin Amyloidosis (ATTR)

Efficacy and Safety of Vutrisiran in Patients with Hereditary Transthyretin-mediated Amyloidosis with Polyneuropathy: Analysis of the East Asian Subpopulation from HELIOS-A

Neurology and Therapy

Author(s)

Jeeyoung Oh, Yoshiki Sekijima, Hideki Mochizuki, et al

 Connect with Alnylam Medical

For further information or questions related to Alnylam's clinical data, connect with Alnylam Medical.

Image
Medical Information

Medical Information

For Medical Information inquiries, please submit your question using the email below.

For country-specific Medical Information contact details, please navigate to the individual country sites located at Alnylam.com.

Image
Adverse Events/Therapy Complaints

Adverse Events/Product Complaints

To report an adverse event or to submit a product complaint, please use the email below.

For country-specific contact details, please navigate to the individual country sites located at Alnylam.com.

Image
Clinical Trials

Clinical Trials

For clinical trial inquiries, please use the contact options below.